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Title Foye's principles of medicinal chemistry / edited by Thomas L. Lemke ... [and others].

Published Philadelphia : Lippincott Williams & Wilkins, [2008]
©2008

Copies

Location Call No. Status
 UniM BioMed  615.19 FOYE    AVAILABLE
Edition 6th ed.
Physical description xiv, 1377 pages : illustrations ; 29 cm
Bibliography Includes bibliographical references and index.
Contents 1. Historical Perspective of Medicinal Chemistry / John L. Neumeyer -- Pt. I. Principles of Drug Discovery -- Ch. 1. Discovery from Natural Products / A. Douglas Kinghorn -- Ch. 2. Drug Design and Relationship of Functional Groups to Pharmacologic Activity / James J. Knittel and Robin M. Zavod -- Ch. 3. Molecular Modeling and In Silico Drug Design / Xiang-Qun (Sean) Xie -- Ch. 4. Receptors and Drug Action / Timothy A. Maher and David A. Johnson -- Ch. 5. Drug Discovery Through Enzyme Inhibition / Stephen Kerr -- Ch. 6. Pharmaceutical Biotechnology - From Nucleic Acids to Personalized Medicine / Ronald E. Reid and Robert D. Sindelar -- Ch. 7. Peptide and Protein Drugs / Michael Mokotoff -- Ch. 8. Antisense Therapeutic Agents / Marilyn Speedie -- Ch. 9. Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics / Sunil S. Jambhekar -- Ch. 10. Drug Metabolism / David A. Williams -- Ch. 11. U.S. Drug Regulation: An Overview / Douglas J. Pisano -- Pt. II. Drug Receptors Affecting Neurotransmission and Enzymes as Catalytic Receptors -- Overview of Drug Receptors: A Perspective / David J. Triggle -- Ch. 12. Drugs Affecting Cholinergic Neurotransmission / E. Kim Fifer -- Ch. 13. Adrenergic Receptors and Drugs Affecting Adrenergic Neurotransmission / Robert K. Griffith -- Ch. 14. Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission / Richard A. Glennon and Malgorzata Dukat-Glennon -- Ch. 15. Amino Acid Neurotransmitters in the Central Nervous System / Timothy J. Maher -- Ch. 16. Inhibitors of Nerve Conduction: Local Anesthetics / Matthias C. Lu -- Ch. 17. Phosphodiesterase Inhibitors / Kevin Dalby -- Pt. III. Pharmacodynamic Agents -- Ch. 18. General Anesthetics / Timothy J. Maher -- Ch. 19. Sedative-Hypnotics / William Soine -- Ch. 20. Antiseizure Agents / Barbara Leduc --
Ch. 21. Antidepressants / David A. Williams -- Ch. 22. Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents / Raymond G. Booth -- Ch. 23. Hallucinogens, Stimulants and Related Drugs of Abuse / Richard A. Glennon -- Ch. 24. Opioid Analgesics / David S. Fries -- Ch. 25. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents / Raymond G. Booth -- Ch. 26. Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs / Ahmed S. Mehanna -- Ch. 27. Diuretics / Gary O. Rankin -- Ch. 28. Angiotensin-Converting Enzyme Inhibitors, Antagonists and Calcium Blockers / Marc Harrold -- Ch. 29. Central and Peripheral Sympatholytics and Vasodilators / David A. Williams -- Ch. 30. Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis / Marc Harrold -- Ch. 31. Antithrombotics, Thrombolytics, Coagulants, and Plasma Extenders / Matthias C. Lu and Thomas L. Lemke -- Ch. 32. Insulin and Drugs Used for the Treatment of Diabetes / Robin M. Zavod, John L. Krstenansky and Bruce L. Currie -- Ch. 33. Adrenocorticoids / Duane D. Miller, Robert W. Brueggemeier and James T. Dalton -- Ch. 34. Thyroid Function and Thyroid Drugs / Ali R. Banijamali -- Ch. 35. Calcium Homeostasis / Robin M. Zavod -- Ch. 36. Nonsteroidal Anti-Inflammatory Drugs / Ronald Borne, Mark Levi and Norman Wilson -- Ch. 37. Antihistamines and Related Antiallergic and Antiulcer Agents / Wendel L. Nelson -- Ch. 38. Antibiotics and Antimicrobial Agents / Lester A. Mitscher, Thomas L. Lemke and Elmer J. Gentry -- Ch. 39. Antiparasitic Agents / Thomas L. Lemke -- Ch. 40. Antifungal Agents / Robert K. Griffith -- Ch. 41. Antimycobacterial Agents / Thomas L. Lemke -- Ch. 42. Cancer and Chemotherapy / Victoria F. Roche -- Ch. 43. Antiviral Agents and Protease Inhibitors / Patrick M. Woster -- Pt. IV. Disease State Management -- Ch. 44. Asthma and Chronic Obstructive Pulmonary Disease / S. William Zito -- Ch. 45. Men's Health / Duane D. Miller, Robert W. Brueggemeier and James T. Dalton -- Ch. 46. Women's Health / Robin M. Zavod -- App. A. pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases -- App. B. pH Values for Tissue Fluids.
Original Version Previous ed.: published as by Thomas A. Williams and Thomas L. Lemke. 2002.
Other author Foye, William O.
Lemke, Thomas L.
Subject Pharmaceutical chemistry.
Variant Title Principles of medicinal chemistry.
Medicinal chemistry.
ISBN 9780781768795
0781768799